A new way of treating heart disease in the world of genetics
Can prove to be a revolutionary achievement
Cells were intensively studied
To be used only after testing
New Delhi: Genetic Scientists have made significant breakthroughs in transforming skin cells.
Scientists of these genetics have been successful in converting these skin cells into cells inside the heart.
With this change, treatment of heart diseases can now be made easier.
It is being judged as a revolutionary achievement in the world of genetics.
Scientists doing research in this direction had studied the structure of heart cells in depth.
It was found that it has about five hundred different genetic variations.
Each of them is responsible for some important work.
With these help, the heart of a human being or any other animal keeps on beating continuously.
Any disturbance in any of these can lead to heart disease and heart attack.
In the course of research, it has also been found that these cells directly have no direct role in the structure of the body’s formation of protins.
They also do not analyze or fragment the structure of protins.
Genetic Scientists of California Institute has done this
After studying their structure in-depth, scientists started working on its alternative.
The work was done at the San Diego School of Medicine in California.
Researchers there found that there are also seven different species of skin cells.
A thorough study of the property defects and genetic structure of all those species discovered them.
The name of this protein is NKX 2-5.
This actually plays an important role in keeping the arteries of the heart active.
The research was then advanced in the same direction.
A dissertation has been published in this month’s journal of Nature Genetics.
Many things have been given in detail in it.
Under the research, a number of genetic processes were discovered which are related to the heart’s proteins.
Scientists have tried to explain in the language of common understanding that this protin i.e. NKX 2-5 actually acts like a switch.
Depending on the instructions received from here, many genes are switched on or off.
After further confirmation of this, further action was taken by senior author of the dissertation,
Dr. Kelly A. Frazer, that the creation of new cells to receive protin instructions was done in skin cells.
Dr. Kelly is a Professor of the Department of Pediatrics and Director of the Genome Medicine Department.
Samples of three generations of the same family were taken
In the initial phase, this research was carried forward by collecting skin samples of seven people from three generations of the same family.
These cells were exposed to a particular type of stale cell.
Stem cells of this variety are called pluripotent stem cells.
They actually play the role of mediator in this change process.
Scientists had already confirmed that stem cells of this variety can increase their own numbers as needed so that the expected target can be achieved.
They also have the property that they are able to identify different cells very well.
With the help of this, the properties of these cells were changed through genetic and other processes to the skin cell.
Due to this change, the skin cells gradually converted into heart cells.
Researchers carefully recorded this change of every round and made necessary corrections.
This constant experiment eventually led to the conversion of skin cells into heart cells.
Even after its success in the laboratory, it will have to undergo several other tests before it can be put into practice.